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Navarixin
CAS No. : 473727-83-2
Biological Activity：Navarixin (SCH 527123) is a potent, allosteric and orally active antagonist of both CXCR1 and CXCR2, with Kd values of 41 nM for cynomolgus CXCR1 and 0.20 nM, 0.20 nM, 0.08 nM for mouse, rat and cynomolgus monkey CXCR2, respectivelly[2].
Research Area：Inflammation/Immunology|Endocrinology
Targets：CXCR
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Small Molecule Immuno-Oncology Compound Library;Drug Repurposing Compound Library;Endocrinology Compound Library;Anti-COVID-19 Compound Library;Orally Active Compound Library;Anti-Prostate Cancer Compound Library;Chemokine Compound Library;
Related Small Molecules:Nicotinamide N-oxide;FC131;CXCR4 antagonist 2;AMG 487 (S-enantiomer);CXCR4 antagonist 6;CXCR2 antagonist 4;VUF11207 fumarate;KRH-3955 hydrochloride;IT1t dihydrochloride;NBI-74330;MSX-130;SCH 546738;Elubrixin;CXCR2 antagonist 2;CXCR2-IN-1;Mavorixafor;HF51116;Reparixin L-lysine salt;HF50731;AZD-5069;AZD8797;BAM-12P;CTCE-0214;Baohuoside I;Ladarixin sodium;CXCR2 antagonist 3
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