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Zetomipzomib maleate
CAS No. : 2170983-62-5
Biological Activity:Zetomipzomib (KZR-616) maleate, a first-in-class immunoproteasome inhibitor, selectively targets the LMP7 (IC50: 39/57 nM=hLMP7/mLMP7) and LMP2 (IC50: 131/179 nM=hLMP7/mLMP7) subunits of the immunoproteasome. Zetomipzomib maleate has the potential for the research of multiple autoimmune diseases[2].
Research Area:Inflammation/Immunology
Targets:Proteasome
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;
Related Small Molecules:Calpeptin;Calpain Inhibitor VI;MG-101;ONX-0914 TFA;MG-115;UK-101;SAP2-IN-1;LXE408;GSK3494245;PR-39;20S Proteasome-IN-1;M3258;PI-1840;Rpn11-IN-1;Delanzomib;Ac-ANW-AMC;Cyclotheonellazole A;Aclacinomycin A;Vimentin-IN-1;DD1;VR23;Tomatine;Gabexate mesylate;Alicapistat;Neurodegenerative Disorder-Targeting Compound 1
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