For research use only. We do not sell to patients.

Propafenone

CAS No. : 54063-53-5

Biological Activity：Propafenone (SA-79), a sodium-channel blocker, acts an antiarrhythmic agent. Propafenone also has high affinity for the β receptor (IC₅₀=32 nM). Propafenone blocks the transient outward current (Ito) and the sustained delayed rectifier K current (Isus) with IC₅₀ values of 4.9 μm and 8.6 μm, respectively^[2]. Propafenone suppresses esophageal cancer proliferation through inducing mitochondrial dysfunction and induce apoptosis^[3].

Research Area：Cancer|Cardiovascular Disease

Targets：Adrenergic Receptor|Sodium Channel|Potassium Channel

Related Small Molecules:Lu AE98134;Todralazine;ARC 239 dihydrochloride;Kv3 modulator 2;Zandatrigine;Yohimbine;Glaucine;Veratridine;Salbutamol;Brompheniramine-d6 maleate;Pinacidil;BI-167107;GX-674;AMP-PNP tetralithium;Talibegron hydrochloride;Dibucaine;IK1 inhibitor PA-6;Arotinolol;SR59230A

About Us:

MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use；
Structurally and synthetically diverse biologically active compounds；
roduct quality is the key to our success and we take pride in offering only the highest-grade products.；
We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.；
Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.；

Structurally and synthetically diverse biologically active compounds；

Customized order volume ranging from milligrams to kilograms scale；

We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.

Top Publications Citing Use of MCE Products