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Cholera toxin

CAS No. : 9012-63-9

Biological Activity：Cholera toxin (Choleragen), an AB(5)-subunit toxin, enters host cells by binding the ganglioside GM1 at the plasma membrane (PM) and travels retrograde through the trans-Golgi Network into the endoplasmic reticulum (ER). Choleragen activates adenylate cyclase by catalyzing ADP-ribosylation of Gs alpha, the stimulatory guanine nucleotide-binding protein^[2].

Research Area：Inflammation/Immunology

Targets：Adenylate Cyclase

Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;Bioactive Compound Library Plus;

Related Small Molecules:NKY80;Fipexide;CB-7921220;TDI-10229;Angiopeptin;Mant-GTPγS;SKF-83566;Forskolin;Lysipressin acetate;TIP 39, Tuberoinfundibular Neuropeptide;Small Cardioactive Peptide B (SCPB);SQ22536;AC1-IN-1;Adenylyl cyclase type 2 agonist-1;TDI-11861;ST034307;LRE1;NKH477;[DPro10] Dynorphin A (1-11), porcine;Forskolin (GMP);[Tyr22] Calcitonin Gene Related Peptide, (22-37), rat;KH7;NB001

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