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GPP78

CAS No. : 1202580-59-3

Biological Activity：GPP78 (CAY10618) is a potent Nampt inhibitor with an IC₅₀ of 3.0 nM for nicotinamide adenine dinucleotide (NAD) depletion. GPP78 is cytotoxic to neuroblastoma cell line SH-SY5Y cells with an IC₅₀ of 3.8 nM by inducing autophagy. GPP78 has anti-cancer and anti-inflammatory effects^[2].

Research Area：Cancer|Inflammation/Immunology

Targets：Autophagy|NAMPT

Related Small Molecules:Teglarinad chloride;CB 300919;GNE-617;NAMPT inhibitor-linker 2;NAMPT degrader-1;Nampt-IN-8;Nampt-IN-3;Nampt-IN-10 TFA;Nampt-IN-7;SBI-797812;LB-60-OF61;Nampt-IN-5;CB30865;NAT;Nampt-IN-1;LB-60-OF61 hydrochloride;STF-118804;OT-82;CHS-828;Nampt-IN-9;(E)-Daporinad;GNE-618

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