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CAIX Inhibitor S4
CAS No. : 1330061-67-0
Biological Activity:CAIX Inhibitor S4 is a potent and selective inhibitor of carbonic anhydrase IX/XII (CA IX/XII), with a Ki of 7 nM and 2 nM, respectively. CAIX Inhibitor S4 also inhibits CA II and CA I (Ki=546 and 5600 nM, respectively). CAIX Inhibitor S4 can inhibit the number of lung metastasis in orthotopic MDA-MB-231 mouse model without affecting primary tumor growth.
Research Area:Cancer
Targets:Carbonic Anhydrase
Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Covalent Screening Library;
Related Small Molecules:Enpp/Carbonic anhydrase-IN-1;hCAIX-IN-8;Phenylsulfamide;Benzolamide;(E)-Dehydrodiconiferyl alcohol;hCAIX/XII-IN-1;CAXII-IN-1;hCAIX/XII-IN-2;hCAIX-IN-12;Girentuximab;hCAII-IN-2;hCAI/II-IN-1;hCAI/II-IN-4;Dichlorphenamide;hCAIX-IN-16;hCAII-IN-1;Sultiame;hCAII-IN-3;Carbonic anhydrase inhibitor 6;hCAXII-IN-4;hCAIX-IN-10;U-104;Carbonic anhydrase inhibitor 4;EMAC10101d
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