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HSP90-IN-13
CAS No. : 2446055-29-2
Biological Activity：HSP90-IN-13 (compound 5k) is a highly potent HSP90 pan inhibitor with an IC50 value of 25.07 nM. HSP90-IN-13 has multi-target activity against EGFR, VEGFR-2 and Topoisomerase-2. HSP90-IN-13 causes cell cycle arrest at G2/M phase and induces apoptosis of MCF-7 cells through mitochondrial-mediated pathway.
Research Area：Cancer
Targets：EGFR|Topoisomerase|HSP|VEGFR|Apoptosis
Related Small Molecules:Physalin A;Bomedemstat ditosylate;(Z)-FeCP-oxindole;Gepotidacin;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;NSC81111;BJE6-106;Dinaciclib;VEGFR-2-IN-24;pp60 (v-SRC) Autophosphorylation Site, Phosphorylated;Ecteinascidin 770;MDM2-p53-IN-15;BMS-690514;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant
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