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BMS-754807
CAS No. : 1001350-96-4
Biological Activity：BMS-754807 is a potent and reversible IGF-1R/IR inhibitor (IC50=1.8 and 1.7 nM, respectively; Ki=<2 nM for both). BMS-754807 also shows potent activities against Met, RON, TrkA, TrkB, AurA, and AurB with IC50 values of 6, 44, 7, 4, 9, and 25 nM, respectively.
Research Area：Cancer|Endocrinology
Targets：Insulin Receptor|IGF-1R
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Differentiation Inducing Compound Library;Endocrinology Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Angiogenesis-Related Compound Library;Anti-Prostate Cancer Compound Library;
Related Small Molecules:AGL-2263;AZ7550 Mesylate;KU14R;Picropodophyllotoxin-d6;SU4984;Chromeceptin;I-OMe-Tyrphostin AG 538;Ganitumab;HNMPA-(AM)3;S961 TFA;OI338;Gastric Inhibitory Peptide, porcine;MSDC 0160;[Tyr0] Gastric Inhibitory Peptide (23-42), human;AVJ16;GIP, human;GSK1838705A;DA-JC4;MSDC-0602K;AG1024;Xentuzumab;Teprotumumab;IGF-I (24-41)
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