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Nemorubicin
CAS No. : 108852-90-0
Biological Activity：Nemorubicin (Methoxymorpholinyl doxorubicin) is a Doxorubicin derivative with potent antitumor activity. Nemorubicin is highly cytotoxic to a variety of tumor cell lines presenting a multidrug-resistant phenotype. Nemorubicin not only intercalate into the duplex DNA, but also result in significant ligands for G-quadruplex DNA segments, stabilizing their structure. Nemorubicin requirs an intact nucleotide excision repair (NER) system to exert its activity[2][3][4].
Research Area：Cancer
Targets：G-quadruplex
Related Screening Libraries:Bioactive Compound Library Plus;
Related Small Molecules:2-Di-1-ASP;MM41;L5-DA;360A;SOP1812;TMPyP4 tosylate;G4/HDAC-IN-1;Pyridostatin hydrochloride;BMVC;Carboxy pyridostatin trifluoroacetate salt;BMVC2
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