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SNIPER(BRD)-1
CAS No. : 2095244-54-3
Biological Activity:SNIPER(BRD)-1, consists of an IAP antagonist LCL-161 derivative and a BET inhibitor, (+)-JQ-1, connected by a linker. SNIPER(BRD)-1 induces the degradation of BRD4 via the ubiquitin-proteasome pathway. SNIPER(BRD)-1 also degrades cIAP1 , cIAP2 and XIAP with IC50s of 6.8 nM, 17 nM, and 49nM, respectively.
Research Area:Cancer
Targets:Epigenetic Reader Domain|SNIPERs
Related Screening Libraries:Bioactive Compound Library Plus;
Related Small Molecules:RVX-297;BRD4 Inhibitor-19;UNC6349 (Ket2);Curcumin;GSK6853;GSK4028;SNIPER(ABL)-039;SR-0813;Inobrodib;Apabetalone;OF-1;I-CBP112;A-485;PLX51107;FKBP12 PROTAC dTAG-7;I-BET151;SNIPER(ABL)-049;GSK040;BRM/BRG1 ATP Inhibitor-4;PBRM1-BD2-IN-5;MI-136;IACS-9571;SF2523;L-Moses dihydrochloride;KB02-JQ1;SNIPER(ABL)-015;GSK620;INCB-057643;Bromodomain IN-1
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