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SB-408124

CAS No. : 288150-92-5

Biological Activity：SB-408124 is a non-peptide OX1 receptor antagonist with K_is of 57 nM and 27 nM in whole cell and membrane, respectively. SB-408124 exhibits 50-fold selectivity over OX2 receptor.

Research Area：Neurological Disease|Endocrinology

Targets：Orexin Receptor (OX Receptor)

Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Neuronal Signaling Compound Library;Covalent Screening Library;Endocrinology Compound Library;Targeted Diversity Library;Human Metabolite Library;

Related Small Molecules:MK-3697;JNJ-54717793;TCS-OX2-29;IPSU;Seltorexant hydrochloride;Orexin B, rat, mouse;SB-649868;Orexin A (human, rat, mouse) (acetate);SB-408124 Hydrochloride;OX2R-IN-1;EMPA;Orexin B, human;SB-334867 free base;MK-1064;Almorexant-13C,d3;YNT-185 dihydrochloride;Orexin 2 Receptor Agonist;[Ala11,D-Leu15]-Orexin B(human);Suntinorexton;Almorexant;SB-674042;Filorexant;Orexin receptor antagonist 4;OXA(17-33) TFA;Lemborexant;Danavorexton

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