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TGR5 Receptor Agonist 3
CAS No. : 2643391-08-4
Biological Activity：TGR5 Receptor Agonist 3 (Compound 19) is a soft-drug G-protein-coupled bile acid receptor 1 (GPBAR1, TGR5) agonist with reduced gallbladder-filling effects (favorable gallbladder safety), with EC50s of 16.4 and 209 nM for hTGR5 and mTGR5, respectively.
Research Area：Metabolic Disease
Targets：G protein-coupled Bile Acid Receptor 1
Related Small Molecules:Hyodeoxycholic acid-d5;Cholic acid 7-sulfate;Deoxycholic acid-13C;Deoxycholic acid sodium hydrate;Taurodeoxycholic acid sodium hydrate;SBI-115;INT-767;INT-777;BAR502;5-HT7R antagonist 1;PEN (human);Hyodeoxycholic acid;SB756050;Deoxycholic acid-d6;BAR501;GPBAR1-IN-3;TC-G 1005;TGR5 Receptor Agonist;CAY10789;FXR/TGR5 agonist 1
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