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PROTAC IDO1 Degrader-1
CAS No. : 2488851-89-2
Biological Activity：PROTAC IDO1 Degrader-1 is the first potent IDO1 (indoleamine 2,3-dioxygenase 1) degrader that hijacks IDO1 to Cereblon E3 ligase to introduce IDO1 into UPS and eventually achieve ubiquitination and degradation (DC50=2.84 μM). PROTAC IDO1 Degrader-1 moderately improves the tumor-killing activity of H ER2 CAR-T cells.
Research Area：Inflammation/Immunology
Targets：Indoleamine 2,3-Dioxygenase (IDO)|PROTACs
Related Screening Libraries:Bioactive Compound Library Plus;
Related Small Molecules:PROTAC Sirt2 Degrader-1;DB0614;PROTAC VEGFR-2 degrader-2;dTAGV-1-NEG;CCT367766 formic;HDAC6 degrader-1;IDO1-IN-14;PROTAC Axl Degrader 2;Coptisine Sulfate;PhosTAC7;MS98;JPS014;PROTAC PARP1 degrader;Coptisine chloride;MD-224;FKBP12 PROTAC dTAG-7;IACS-8968;Indoximod;SJ10542;IDO-IN-12;MS8815;RIP2 Kinase Inhibitor 4;PROTAC EGFR degrader 7;SJ995973;CC-885-CH2-PEG1-NH-CH3;IDO1-IN-16;dFKBP-1;MI-389;BSJ-4-116;MS4078
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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