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CCR2 antagonist 5

CAS No. : 1228650-83-6

Biological Activity：CCR2 antagonist 5 is a selective, orally active hCCR2 inhibitor with good binding affinity (IC₅₀=37 nM) and potent functional antagonism (chemotaxis IC₅₀=30 nM). CCR2 antagonist 5 displays a K_i of 9.6 µM for mCCR2 binding. CCR2 antagonist 5 can be used in the research of inflammatory disease.

Research Area：Inflammation/Immunology

Targets：CCR

Related Small Molecules:LMD-009;PF-04634817 succinate;Vercirnon;CKLF1-C27;Bindarit;CCR6 antagonist 1;CCR6 inhibitor 1;CCR4-351 hydrochloride;BI 639667;ML604086;CCR4 antagonist 3-1;AZD2423;AZD2098;AZD-1678;R243;RS102895 hydrochloride;Vicriviroc maleate;BMS-639623;AZD-4818;INCB 3284 dimesylate;Maceneolignan H;CKLF1-C27 TFA;CCR3 antagonist 1;C-021;INCB3344;RPT193

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