(-)-Hydroxycitric acid lactone

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(-)-Hydroxycitric acid lactone

CAS No. : 27750-13-6

Biological Activity:(-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent and a popular weight loss food supplement. (-)-Hydroxycitric acid lactone is a potent inhibitor of ATP-citrate lyase. (-)-Hydroxycitric acid lactone catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA, limits the availability of acetyl-CoA units required for fatty acid synthesis[2].

Research Area:Metabolic Disease

Targets:ATP Citrate Lyase

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Related Small Molecules:(-)-Hydroxycitric acid;MEDICA16;Bempedoic acid;SB 204990;Hydroxycitric acid tripotassium hydrate;2-Furoic acid;BMS-303141;NDI-091143

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