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Doxofylline

CAS No. : 69975-86-6

Biological Activity：Doxofylline is an orally active PDE IV inhibitor and A1AR antagonist. Doxofylline reduces inflammation in epithelial cells via inhibiting mitochondrial ROS production and amelioration of multiple cellular pathways (NLRP3-TXNIP inflammasome activation). Doxophylline can be used in studies of asthma, chronic obstructive pulmonary disease, and bronchospasm^[2][3].

Research Area：Inflammation/Immunology

Targets：Phosphodiesterase (PDE)|Reactive Oxygen Species|Adenosine Receptor

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