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TBAJ-587

CAS No. : 2252316-16-6

Biological Activity：TBAJ-587, a potent anti-tuberculosis agent, inhibits M.tb strain H37Rv growth with MIC₉₀s of 0.006 and <0.02 µg/mL in MABA and LORA assay, respectively. TBAJ-587 inhibits hERG channel minimally, attenuates inhibition of the cardiac potassium channel protein coded by the hERG, which is important for cardiac repolarization.

Research Area：Infection|Cardiovascular Disease

Targets：Bacterial

Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Clinical Compound Library;Anti-Cardiovascular Disease Compound Library;Antibacterial Compound Library;

Related Small Molecules:Sandramycin;LLO (91-99);Gepotidacin;Oritavancin;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Isouvaretin;Antibacterial agent 99;Nafcillin;Antitubercular agent-28;Ochromycinone;Staurosporine;Nucleocidin;(±)-Leucine-13C-1;Ciclopirox-d11;Ciclopirox olamine;Clotrimazole-d5;SQ109;Neomycin sulfate;Bauer-7-ene-3β,16α-diol;Aminothiazole

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