For research use only. We do not sell to patients.
L-Buthionine-(S,R)-sulfoximine hydrochloride
Biological Activity：L-Buthionine-(S,R)-sulfoximine hydrochloride is a cell-permeable, potent, fast acting, orally active and irreversible inhibitor of g-glutamylcysteine synthetase and depletes cellular glutathione levels. The IC50 value of L-Buthionine-(S,R)-sulfoximine on melanoma, breast and ovarian tumor specimens are 1.9 μM, 8.6 μM, and 29 μM, respectively[2].
Research Area：Cancer|Metabolic Disease
Targets：Ferroptosis
Related Small Molecules:CIL56;DB0614;Ciclopirox-d11;Ciclopirox olamine;Curcumin;(-)-Epicatechin;Eugenol-d3;Artemisinin-d3;MMRi62;UAMC-3203;L-Glutamic acid-15N,d5;Chalcones A-N-5;Pifithrin-β hydrobromide;PD146176;Roxadustat;Matrine;Liproxstatin-1;Hemin;L-Glutamic acid monosodium salt;Acetylcysteine-d3;Pifithrin-α hydrobromide
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Structurally and synthetically diverse biologically active compounds；
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