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GW791343 trihydrochloride
CAS No. : 309712-55-8
Biological Activity：GW791343 trihydrochloride is a potent human P2X7 receptor negative allosteric modulator (exhibits species-specific activity), produces a non-competitive antagonist effect on human P2X7 receptor, with a pIC50 of 6.9-7.2. GW791343 trihydrochloride can enhance ATP rhythm. GW791343 trihydrochloride can be used in study of neurological disease[2].
Research Area：Neurological Disease
Targets：P2X Receptor
Related Small Molecules:Gefapixant citrate;JNJ-47965567;AF-353;Oxatomide;AZ10606120 dihydrochloride;Taspine;A-317491;NF449 octasodium;A-804598;P2X receptor-1;Aurintricarboxylic acid;Minodronic acid;NF023 hexasodium;A 438079 hydrochloride;KN-62;Opiranserin;GW791343 dihydrochloride;5-BDBD;NF279;Lu AF27139;JNJ-55308942;PPNDS tetrasodium;8-Bromo-ATP;P2X3 antagonist 36;NF110;BAY-1797;Ro-51;P2X3 antagonist 37
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