Takeda-6D

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Takeda-6D

CAS No. : 1125632-93-0

Biological Activity:Takeda-6D (compound 6d) is an orally active and potent BRAF/VEGFR2 inhibitor, with IC50 values of 7.0 and 2.2 nM, respectively. Takeda-6D shows antiangiogenesis by suppressing the VEGFR2 pathway in 293/KDR and VEGF-stimulated HUVEC cells.Takeda-6D shows significant suppression of ERK1/2 phosphorylation. Takeda-6D shows antitumor activity.

Research Area:Cancer

Targets:PERK|Raf|VEGFR

Related Small Molecules:(Z)-FeCP-oxindole;Avutometinib;VEGFR-2-IN-24;BMS-690514;PROTAC VEGFR-2 degrader-2;AZ 628;Henatinib;PI3K/VEGFR2-IN-1;Hydroxytanshinone IIA;Chiauranib;Foretinib;ZM323881 hydrochloride;PTC299;ENMD-2076 Tartrate;Aflibercept;SU5408;MAZ51;R1530;Everafenib;AZD2932;R916562

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