For research use only. We do not sell to patients.
5-O-Demethylnobiletin
CAS No. : 2174-59-6
Biological Activity:5-O-Demethylnobiletin (5-Demethylnobiletin), a polymethoxyflavone isolated from Citrus jambhiri Lush., is a direct inhibition of 5-LOX (IC50=0.1 μM), without affecting the expression of COX-2. 5-O-Demethylnobiletin (5-Demethylnobiletin) has anti-inflammatory activity, inhibits leukotriene B (4)(LTB4) formation in rat neutrophils and elastase release in human neutrophils with an IC50 of 0.35 μM.
Research Area:Inflammation/Immunology|Neurological Disease|Cancer
Targets:Leukotriene Receptor|Lipoxygenase
Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;GPCR/G Protein Compound Library;Immunology/Inflammation Compound Library;Metabolism/Protease Compound Library;Natural Product Library;Anti-Cancer Compound Library;Lipid Compound Library;Ferroptosis Compound Library;Medicine Food Homology Compound Library;Traditional Chinese Medicine Active Compound Library; Lipid Metabolism Compound Library ;Food-Sourced Compound Library ;Anti-Cancer Natural Product Library;Anti-inflammatory Traditional Chinese Medicine Active Compound Library;Plant-Sourced Natural Product Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;
Related Small Molecules:COX-2/5-LOX-IN-3;Pranlukast-d4;Verlukast-d6;A-69412;5-LOX-IN-1;Atreleuton;S-(+)-Marmesin;Ablukast;CP-96486;MK-886;Malotilate;Phenidone;2-TEDC;BW B70C;ALOX15-IN-2;PGS-IN-1;BIIL-260 hydrochloride;Pranlukast;ALOX15-IN-1;Ro 3-1314;Isothymusin;γ-Linolenic acid ethyl ester;REV 5901;Indirubin-3′-monoxime;U-75302;RS-601;S-2474
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
About Us:
- MedChemExpress (MCE) offers a wide range of high-quality research chemicals and biochemicals (novel life-science reagents, reference compounds and natural compounds) for scientific use;
- Structurally and synthetically diverse biologically active compounds;
- roduct quality is the key to our success and we take pride in offering only the highest-grade products.;
- We provide HNMR, LC-MS, HPLC, stability testing and activity assays of our products to clients.;
- Product identity, quality, purity and activity are assured by our robust quality control programs and procedures.;
- Customized order volume ranging from milligrams to kilograms scale;
Structurally and synthetically diverse biologically active compounds;
We provide customer-oriented services. To explore more, please contact us at [email protected]. Our team will gladly assist you.