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DTHIB
CAS No. : 897326-30-6
Biological Activity：DTHIB is a direct and selective heat shock factor 1 (HSF1) inhibitor with a Kd of 160 nM for DTHIB binding to the HSF1 DNA binding domain (DBD). DTHIB inhibits HSF1 cancer gene signature (HSF1 CaSig) and selectively stimulates degradation of nuclear HSF1. DTHIB has potently anticancer activities and can be used for prostate cancer research.
Research Area：Cancer
Targets：HSP
Related Screening Libraries:Covalent Screening Library Plus;Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Metabolism/Protease Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Covalent Screening Library;Cytoskeleton Compound Library;Transcription Factor-Targeted Library;Anti-Prostate Cancer Compound Library;
Related Small Molecules:6BrCaQ;116-9e;Paeoniflorin;HDAC/HSP90-IN-4;Debio 0932;MKT-077;Ethoxyquin;Cemdomespib;Apatorsen;HS-131;CH5138303;Pimitespib;NCT-58;MPC-0767;Retaspimycin;BOLD-100;Onalespib;HSP90-IN-12;Palmitic acid-1-13C;Palmitic acid-d3;Feretoside;Palmitic acid-d9;Palmitic acid-13C2;Gamitrinib TPP;JG-98;Gedunin;Rocaglamide;Palmitic acid-13C sodium;AMP-PCP
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