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DC4SMe
CAS No. : 615538-47-1
Biological Activity:DC4SMe, a phosphate prodrug of cytotoxic DNA alkylator DC4, can be used in the synthesis of Antibody-drug Conjugate (ADC). DC4SMe exhibits IC50s of 1.9 nM, 2.9 nM, and 1.8 nM for Ramos, Namalwa, and HL60/s cancer cells, respectively. DC4SMe can be used for the targeted treatment of cancer.
Research Area:Cancer
Targets:ADC Cytotoxin
Related Small Molecules:Sandramycin;(R)-Camptothecin-d5;Dolastatin 10;INX-SM-56;DC10SMe;Rebeccamycin;Duocarmycin TM;Fmoc-MMAE;Taltobulin;N-Me-L-Ala-maytansinol;CC-885-CH2-PEG1-NH-CH3;Camptothecin;Maytansinol;Tomaymycin DM;Hemiasterlin derivative-1;SGD-1882;Corixetan;Duostatin 5;PROTAC BRD4 Degrader-13;Dxd-d5;Tubulysin IM-1;Duocarmycin SA;Ansamitocin P 3′;PNU-159682 carboxylic acid;Duocarmycin DM free base
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