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Cabamiquine succinate

CAS No. : 2444781-71-7

Biological Activity：Cabamiquine (DDD107498) succinate is a potent and orally active antimalarial agent, inhibits multiple life-cycle stages of the parasite, with an EC₅₀ of 1 nM against P. falciparum 3D7. Cabamiquine succinate inhibits protein synthesis by targeting eEF2/CaMKIII, with an EC₅₀ of 2 nM for WT-PfeEF2.

Research Area：Infection

Targets：Parasite|CaMK

Related Screening Libraries:Clinical Compound Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Kinase Inhibitor Library;Neuronal Signaling Compound Library;Clinical Compound Library;Orally Active Compound Library;Antiparasitic Compound library;Targeted Diversity Library;

Related Small Molecules:(+)-Isopulegol;DB0614;SR9186;Antileishmanial agent-2;Azlocillin sodium salt;SQ109;Trypanothione synthetase-IN-3;Pyrantel;α-Terpinene;Dehydrocorydaline;Niclosamide monohydrate;Febrifugine dihydrochloride;Antimalarial agent 15;Cycloguanil hydrochloride;Anti-infective agent 6;Morantel tartrate;Sulfiram;UCB7362;Retro-2;PfDHODH-IN-2

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