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Lufotrelvir
CAS No. : 2468015-78-1
Biological Activity:Lufotrelvir (PF-07304814), a phosphate prodrug of PF-00835231, acts as a potent 3CLpro protease (Mpro) inhibitor with SARS-CoV-2 antiviral activity. Lufotrelvir binds and inhibits SARS-CoV-2 3CLpro activity with a Ki of 174nM. Lufotrelvir is promising single antiviral agent and also can be used for the research of combination with other antivirals that target other critical stages of the coronavirus life cycle.
Research Area:Infection
Targets:SARS-CoV
Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;
Related Small Molecules:SARS-CoV-2-IN-33;GRL-0496;Grazoprevir potassium salt;SARS-CoV-2-IN-19;Molnupiravir;SARS-CoV-2 Mpro-IN-3;MM3122;Ketotifen fumarate;SARS-CoV-2-IN-16;Thapsigargin;INSCoV-614(1B);Anti-SARS-CoV-2 Spike mAb (CR3022);GNF-2;Bemnifosbuvir hemisulfate;Kansuinine B;Proglumetacin;HCoV-229E-IN-1
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