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Rapamycin

CAS No. : 53123-88-9

Biological Activity：Rapamycin (Sirolimus; AY 22989) is a potent and specific mTOR inhibitor with an IC₅₀ of 0.1 nM in HEK293 cells. Rapamycin binds to FKBP12 and specifically acts as an allosteric inhibitor of mTORC1. Rapamycin is an autophagy activator, an immunosuppressant^[2].

Research Area：Cancer

Related Screening Libraries:Covalent Screening Library Plus;Natural Product Library Plus;Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Apoptosis Compound Library;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;Metabolism/Protease Compound Library;PI3K/Akt/mTOR Compound Library;Stem Cell Signaling Compound Library;Natural Product Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Antiviral Compound Library;CNS-Penetrant Compound Library;Autophagy Compound Library;Human Endogenous Metabolite Compound Library;Peptidomimetic Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Covalent Screening Library;Antioxidant Compound Library;Differentiation Inducing Compound Library;Reprogramming Compound Library;Macrocyclic Compound Library;Lipid Compound Library;Oxygen Sensing Compound Library;Antifungal Compound Library;Antibacterial Compound Library;Anti-COVID-19 Compound Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Orally Active Compound Library;Chemical Probe Library;Glutamine Metabolism Compound Library;FDA Approved & Pharmacopeial Drug Library;Antibiotics Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Microbial Metabolite Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Lipid Metabolism Compound Library ;Glucose Metabolism Compound Library;Anti-Liver Cancer Compound Library ;Rare Diseases Drug Library;Anti-Colorectal Cancer Compound Library ;Children’s Drug Library;Anti-Cancer Natural Product Library;Protein-protein Interaction Inhibitor Library;EMA-Approved Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Non-steroidal Anti-Inflammatory Compound Library;Anti-Aging Natural Product Library;Cancer Stem Cells Compound Library;

Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Antifungal agent 20;Nicotinamide N-oxide;3-Hydroxyglutaric acid-d5;DPPC-d62;SDMA-d6;2-Mercaptobenzothiazole;Sandramycin;LLO (91-99);N-Acetyl-L-glutamic acid-d5;Gepotidacin;(3R,5S)-3-Hydroxy Cotinine-d3;Biliverdin hydrochloride;Oritavancin;Monascorubrin;Azlocillin sodium salt;D-Glucose-13C,d1-3;2,3-Diaminopropionic acid hydrochloride;Docosanoic acid-d3;Choline-d6 chloride;Herbimycin A

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