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Tesofensine

CAS No. : 195875-84-4

Biological Activity：Tesofensine (NS-2330) is a triple monoamine reuptake inhibitor inducing a potent inhibition of the re-uptake process in the synaptic cleft of the neurotransmitters dopamine (DA; IC₅₀=6.5 nM), norepinephrine (NE;IC₅₀=1.7 nM), and serotonin (5-HT;IC₅₀=11 nM), and with potentials as an anti-obesity agent. Tesofensine is a CNS acting anti-obesity agent^[2].

Research Area：Metabolic Disease

Targets：Dopamine Transporter|Serotonin Transporter

Related Small Molecules:Diclofensine;Ansofaxine;13-Hydroxyisobakuchiol;Edivoxetine hydrochloride;DSP-1053;Fipexide;Vanoxerine;Azaphen dihydrochloride monohydrate;Wf-516;Nitroxazepine;SPD-473 citrate;Indalpine;Nardoguaianone J;Diclofensine-d3 hydrochloride;Pseudoisocyanine iodide;Roxindole;Cinchonidine;Bisacodyl;AHN 1-055 hydrochloride;BMS-466442;Eplivanserin (mixture)

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