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PERK-IN-5
CAS No. : 2616821-91-9
Biological Activity：PERK-IN-5 is a highly potent, selectively and orally bioavailable PERK inhibitor (IC50s of 2 and 9 nM for PERK and p-eIF2α, respectively). PERK-IN-5 can significantly inhibit tumor growth in the 786-O renal cell carcinoma xenograft tumor model.
Research Area：Cancer
Targets：PERK
Related Screening Libraries:Bioactive Compound Library Plus;
Related Small Molecules:AMG PERK 44;GSK2656157;ONO-8130;PERK-IN-3;VU0424465;7DG;ML291;MEK/PI3K-IN-1;Takeda-6D;GSK2606414;PERK-IN-2;MEK/PI3K-IN-2;JDQ-443;MK-28;Derrone;ISRIB (trans-isomer);GSK143 dihydrochloride;YF135;CCT020312;PERK-IN-4-d3;PERK-IN-4
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