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DX3-213B

CAS No. : 2749555-66-4

Biological Activity：DX3-213B is a highly potent, orally active oxidative phosphorylation (OXPHOS) complex I inhibitor (IC₅₀=3.6 nM). DX3-213B impairs ATP generation (IC₅₀=11 nM), and blocks MIA PaCa-2 cell growth (GI₅₀=11 nM). DX3-213B is used for the research of the pancreatic cancer.

Research Area：Cancer

Targets：Mitochondrial Metabolism

Related Screening Libraries:Bioactive Compound Library Plus;Metabolism/Protease Compound Library;Stem Cell Signaling Compound Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Reprogramming Compound Library;Orally Active Compound Library;Glutamine Metabolism Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Parkinson’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Mitochondria-Targeted Compound Library;Glucose Metabolism Compound Library;Cuproptosis Compound Library;Cancer Stem Cells Compound Library;

Related Small Molecules:MitoTam bromide, hydrobromide;MitoTEMPO hydrate;NL-1;Thiabendazole-d4;D-Histidine;Mito-apocynin (C2);Fumarate hydratase-IN-2 sodium salt;Schaftoside;Daidzin;Azemiglitazone;Tempo;Idebenone;Menadiol;CTPI-2;Senecionine acetate;Antimalarial agent 14;Mito-apocynin (C11);OXPHOS-IN-1;Mitochondrial respiration-IN-1 hydrobromide;Tubulin/HDAC-IN-1;Clidanac;IMT1;Nonactin;RYL-552;DX2-201;MSDC 0160

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