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Mitapivat
CAS No. : 1260075-17-9
Biological Activity：Mitapivat (AG-348) is an orally active pyruvate kinase allosteric activator. Mitapivat increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes, shows the potential to restore the activity of PK (pyruvate kinase)-deficient glycolytic pathways. Mitapivat can be used in study of PK deficiency[2][3].
Research Area：Metabolic Disease
Targets：Pyruvate Kinase
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Kinase Inhibitor Library;Metabolism/Protease Compound Library;FDA-Approved Drug Library;Drug Repurposing Compound Library;Glycolysis Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Cancer Metabolism Compound Library;Glucose Metabolism Compound Library;Targeted Diversity Library;Rare Diseases Drug Library;
Related Small Molecules:TEPP-46;Etavopivat;Alkannin;PKM2-IN-3;PKM2-IN-1;PKM2 activator 3;PKR-IN-2;PKR activator 2;PKM2 activator 5;FX-11;PKM2 activator 4;DASA-58;TEPC466;PKM2 activator 2;PKR activator 1
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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