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Olomoucine
CAS No. : 101622-51-9
Biological Activity:Olomoucine is an ATP competitive inhibitor of CDKs. Olomoucine is a purine (HY-34431) derivative and inhibits CDC2/cyclin B, Cdk2/cyclin A, Cdk2/cyclin E (both IC50=7 µM), CDK/p35 kinase (IC50=3 µM) and ERK1/p44 MAP kinase (IC50=25 µM)[2]. Olomoucine regulates cell cycle and shows anti-melanin tumor activity[3][4].
Research Area:Others
Targets:CDK
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