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Floxuridine
CAS No. : 50-91-9
Biological Activity：Floxuridine (5-Fluorouracil 2′-deoxyriboside) is a pyrimidine analog and known as an oncology antimetabolite. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage by activating the ATM and ATR checkpoint signaling pathways in vitro. Floxuridine is a extreamly potent inhibitor for S. aureus infection and induces cell apoptosis[2]. Floxuridine has antiviral effects against HSV and CMV[3].
Research Area：Cancer|Infection
Targets：HSV|Nucleoside Antimetabolite/Analog|CMV|DNA/RNA Synthesis|Bacterial|Apoptosis
Related Screening Libraries:Covalent Screening Library Plus;Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Anti-Infection Compound Library;Apoptosis Compound Library;Cell Cycle/DNA Damage Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Antiviral Compound Library;Anti-Aging Compound Library;Drug Repurposing Compound Library;Covalent Screening Library;Reprogramming Compound Library;Nucleotide Compound Library;Antibacterial Compound Library;Anti-COVID-19 Compound Library;NMPA-Approved Drug Library;FDA Approved & Pharmacopeial Drug Library;Anti-Lung Cancer Compound Library;Drug-Induced Liver Injury (DILI) Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Liver Cancer Compound Library ;Chemotherapy Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;
Related Small Molecules:Physalin A;Bomedemstat ditosylate;Sandramycin;LLO (91-99);Gepotidacin;Enpp/Carbonic anhydrase-IN-1;Isoborneol;GK563;Calpeptin;Oritavancin;Lobetyolin;pUL89 Endonuclease-IN-1;m7GpppCpG;Azlocillin sodium salt;Herbimycin A;Antibacterial agent 45;Leucomycin;Ametantrone;Isouvaretin;BJE6-106
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