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BC1618

CAS No. : 2222094-18-8

Biological Activity：BC1618, an orally active Fbxo48 inhibitory compound, stimulates Ampk-dependent signaling (via preventing activated pAmpkα from Fbxo48-mediated degradation). BC1618 promotes mitochondrial fission, facilitates autophagy and improves hepatic insulin sensitivity.

Research Area：Metabolic Disease|Inflammation/Immunology

Targets：Mitophagy|E1/E2/E3 Enzyme|AMPK

Related Screening Libraries:Bioactive Compound Library Plus;Epigenetics Compound Library;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;Metabolism/Protease Compound Library;PI3K/Akt/mTOR Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Antioxidant Compound Library;Oxygen Sensing Compound Library;Ubiquitination Compound Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Orally Active Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Mitochondria-Targeted Compound Library;Lipid Metabolism Compound Library ;Glucose Metabolism Compound Library;

Related Small Molecules:AMPK activator 4;UBE2T/FANCL-IN-1;Curcumin;Melatonin-d3;ZLN024;p53 and MDM2 proteins-interaction-inhibitor (racemic);Navtemadlin;YLF-466D;MD-224;BAY-3827;DI-1859;Resveratrol;3α-Hydroxymogrol;MX69;RG7112;Clioquinol;HTH-01-015;Teslexivir;TRAF6 peptide;Betulinic acid;AM-8735;NAcM-OPT;Matrine

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