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Impurity B of Calcitriol
CAS No. : 66791-71-7
Biological Activity：Impurity B of Calcitriol, Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) is the hormonally active form of vitamin D, Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor (VDR).
IC50 value:
Target: vitamin D receptor
Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) displays calcemic actions. Calcitriol stimulates intestinal and renal Ca2+ absorption and regulates bone Ca2+ turnover. Calcitriol (1,25-Dihydroxyvitamin D3; Rocaltrol )exhibits antitumor activity; Calcitriol(1,25-Dihydroxyvitamin D3; Rocaltrol ) inhibits in vivo and in vitro cell proliferation in a wide range of cells including breast, prostate, colon, skin and brain carcinomas and myeloid leukemia cells.
Research Area：Cancer
Targets：VD/VDR
Related Screening Libraries:Bioactive Compound Library Plus;
Related Small Molecules:Atocalcitol;VD3-d6;Dihydrotachysterol;Tacalcitol;Impurity F of Calcipotriol;MeTC7;(24R)-MC 976;VDR agonist 1;TEI-9648;CB1151;MC 1046;1alpha, 25-Dihydroxy VD2-13C2;Secalciferol;5,6-trans-Vitamin D3;Chol-5-en-24-al-3β-ol;Maxacalcitol-d6;Vitamin D3-13C3;Vitamin D3-D7;Vitamin D4;Vitamin D2-d6
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