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Linopirdine

CAS No. : 105431-72-9

Biological Activity：Linopirdine (DuP 996) is an orally active, selective M-type K⁺ current (IM; Kv7; KCNQ Channels) inhibitor with an IC₅₀ of 2.4 μM. Linopirdine is a TRPV1 agonist. Linopirdine, a putative cognition enhancing drug, increases acetylcholine release in rat brain tissue^[2]^[3].

Research Area：Neurological Disease

Targets：TRP Channel|Potassium Channel

Related Screening Libraries:Bioactive Compound Library Plus;Membrane Transporter/Ion Channel Compound Library;Neuronal Signaling Compound Library;Anti-Alzheimer’s Disease Compound Library;Neurodegenerative Disease-related Compound Library;Mechanoreceptors Compound Library;Potassium Channel Compound Library;Human Metabolite Library;

Related Small Molecules:V116517;GSK2332255B;Pregnenolone monosulfate sodium;Kv3 modulator 2;TRPC5-IN-4;OptoBI-1;Brompheniramine-d6 maleate;Pinacidil;SB-705498;AMP-PNP tetralithium;IK1 inhibitor PA-6;TRPC3/6-IN-1;ABT-239;Pyr3;VU590;Domiphen bromide;Asivatrep;Mesoridazine benzenesulfonate;Tetrandrine;20(S)-Ginsenoside Rg3;(S)-(+)-Modafinic acid-d5;Ononetin;TRPM8 antagonist 3;FEMA 4809;Ketanserin;Hydroxy-α-sanshool

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