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3,6-DMAD hydrochloride

Biological Activity：3,6-DMAD hydrochloride, an acridine derivative, is a potent IRE1α-XBP1s pathway inhibitor. 3,6-DMAD hydrochloride promotes IL-6 secretion via the IRE1α-XBP1s pathway. 3,6-DMAD hydrochloride inhibits IRE1α oligomerization and endoribonuclease (RNase) activity. 3,6-DMAD hydrochloride can be used for research of cancer^[2].

Research Area：Cancer

Targets：IRE1

Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Kinase Inhibitor Library;Anti-Cancer Compound Library;Anti-Aging Compound Library;Endoplasmic Reticulum Stress Compound Library;Anti-Blood Cancer Compound Library;Antidepressant Compound Library;Anti-Prostate Cancer Compound Library;

Related Small Molecules:MKC8866;IXA4;4μ8C;GSK2850163 hydrochloride;B I09;IRE1α kinase-IN-3;IXA6;GSK2850163 (S enantiomer);IRE1α kinase-IN-5;KIRA6;MKC3946;3,6-DMAD dihydrochloride;Kira8;PAIR2;IRE1α kinase-IN-2;Toyocamycin;IRE1α kinase-IN-4;KIRA-7;KIRA9;STF-083010;IRE1α kinase-IN-1;MKC9989

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