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BRD6989
CAS No. : 642008-81-9
Biological Activity：BRD6989, an analog of the natural product cortistatin A (dCA), inhibits CDK8 and upregulates IL-10. BRD6989 selectively binds a complex of CDK8 with an IC50 of ~200 nM. BRD6989 inhibits the kinase activity of recombinant CDK8 or CDK19 complexes.
Research Area：Inflammation/Immunology
Targets：Interleukin Related|CDK
Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;Anti-Aging Compound Library;Anti-Breast Cancer Compound Library;Anti-Blood Cancer Compound Library;Angiogenesis-Related Compound Library;Targeted Diversity Library;Cancer Stem Cells Compound Library;
Related Small Molecules:DB0614;AX-024;Dinaciclib;SNS-032;CC-671;Ginsenoside F3;(E/Z)-Zotiraciclib;Perakizumab;CDK1-IN-4;CCT-251921;BS-181;Samuraciclib hydrochloride hydrate;PNRI-299;T025;Flavopiridol;CDK8-IN-3;CDK9-IN-12;FLT3/CDK4-IN-1;CTX-471;Ac-YVAD-CHO;GFB-12811;GSK 3 Inhibitor IX;Deucravacitinib;Eciruciclib;CDK-IN-6;Lerociclib dihydrochloride;CDK4/6-IN-13;ON-013100;(2S,3R)-Voruciclib hydrochloride
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