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Vacuolin-1

CAS No. : 351986-85-1

Biological Activity：Vacuolin-1 is a potent and cell-permeable lysosomal exocytosis inhibitor. Vacuolin-1 blocks the Ca²⁺-dependent exocytosis of lysosomes and prevents the release of lysosomal content without affecting the process of resealing. vacuolin‐1 is a potent and selective PIKfyve inhibitor and inhibits late‐stage autophagy by impairing lysosomal maturation^[2].

Research Area：Cancer

Targets：Autophagy|PIKfyve

Related Screening Libraries:Bioactive Compound Library Plus;Kinase Inhibitor Library;PI3K/Akt/mTOR Compound Library;Anti-Cancer Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Oxygen Sensing Compound Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Glucose Metabolism Compound Library;Targeted Diversity Library;Cancer Stem Cells Compound Library;

Related Small Molecules:APY0201;Apilimod;PIKfyve-IN-1;YM-201636;MOMIPP

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