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Esculetin
CAS No. : 305-01-1
Biological Activity：Esculetin is an active ingredient extracted mainly from the bark of Fraxinus rhynchophylla. Esculetin inhibits platelet-derived growth factor (PDGF)-induced airway smooth muscle cells (ASMCs) phenotype switching through inhibition of PI3K/Akt pathway. Esculetin has antioxidant, antiinflammatory, and antitumor activities.
Research Area：Cancer|Inflammation/Immunology
Targets：Akt|PI3K
Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Immunology/Inflammation Compound Library;Kinase Inhibitor Library;PI3K/Akt/mTOR Compound Library;Stem Cell Signaling Compound Library;Natural Product Library;Anti-Cancer Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Antioxidant Compound Library;Differentiation Inducing Compound Library;Oxygen Sensing Compound Library;Medicine Food Homology Compound Library;Phenols Library;Glycolysis Compound Library;Cytoskeleton Compound Library;Glutamine Metabolism Compound Library;Traditional Chinese Medicine Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Breast Cancer Compound Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Anti-Cancer Metabolism Compound Library;Anti-Obesity Compound Library;Angiogenesis-Related Compound Library;Glucose Metabolism Compound Library;Food-Sourced Compound Library ;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;Anti-Cancer Natural Product Library;Anti-inflammatory Traditional Chinese Medicine Active Compound Library;Plant-Sourced Natural Product Library;Human Metabolite Library;Anti-Prostate Cancer Compound Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;Coagulation and Anti-coagulation Compound Library;
Related Small Molecules:Akt/NF-κB/JNK-IN-1;Umbralisib hydrochloride;Topoisomerase I/II inhibitor 3;Cyclovirobuxine D;Rigosertib sodium;Tenalisib R Enantiomer;AKTide-2T;PI3kδ inhibitor 1;Sennidin A;PI3K/VEGFR2-IN-1;MS98;PP2A Cancerous-IN-1;1,3-Dicaffeoylquinic acid;PI3Kδ-IN-1;PI-103-d8;PI3Kα-IN-8;Artemisiane E;PI-103 Hydrochloride;IC-87114;PI3K/mTOR Inhibitor-6;Artemisinin-d3;PI3K-IN-10;SF2523;AS1949490;PI3K-IN-29;TD52 dihydrochloride;PI3K/mTOR Inhibitor-1;LM22B-10;PI3K-IN-26
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