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(S,R,S)-AHPC-C5-COOH
CAS No. : 2267282-19-7
Biological Activity：(S,R,S)-AHPC-C5-COOH (VH032-C5-COOH) is a synthesized E3 ligase ligand-linker conjugate, contains the VH032 VHL-based ligand and a linker to form PROTACs. VH-032 is a selective and potent inhibitor of VHL/HIF-1α interaction with a Kd of 185 nM, has the potential for the study of anemia and ischemic diseases.
Research Area：Cancer
Targets：HIF/HIF Prolyl-Hydroxylase|E3 Ligase Ligand-Linker Conjugates
Related Small Molecules:cIAP1 Ligand-Linker Conjugates 6 hydrochloride;TC-S 7009;Glucosamine-13C hydrochloride;HIF1-IN-3;Prolyl Hydroxylase inhibitor 1;(S,R,S)-AHPC-Me-C10-NH2;Glucosamine-13C6,15N hydrochloride;HIF-PHD-IN-1;cIAP1 Ligand-Linker Conjugates 2;AKBA;Glutarimide-Isoindolinone-NH-PEG3-COOH;cIAP1 Ligand-Linker Conjugates 4;LW6;(S,R,S)-AHPC-Me-C7 ester;(S,R,S)-AHPC-C2-PEG4-N3;HIF-2α-IN-5;HIF-1/2α-IN-2;GEM-5;cIAP1 Ligand-Linker Conjugates 5;HIF-1/2α-IN-1;Roxadustat;cIAP1 Ligand-Linker Conjugates 7;cIAP1 Ligand-Linker Conjugates 16;Daprodustat;(S,R,S)-AHPC-C8-NH2 hydrochloride;Acetylarenobufagin;Zifcasiran;Acriflavine hydrochloride;cIAP1 Ligand-Linker Conjugates 8;(S,R,S)-AHPC-PEG4-NH2;BAY 87-2243
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