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CD532 hydrochloride
Biological Activity：CD532 hydrochloride is a potent Aurora A kinase inhibitor with an IC50 of 45 nM. CD532 hydrochloride has the dual effect of blocking Aurora A kinase activity and driving degradation of MYCN. CD532 hydrochloride also can directly interact with AURKA and induces a global conformational shift. CD532 hydrochloride can be used for the research of cancer[2].
Research Area：Cancer
Targets：Aurora Kinase
Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Epigenetics Compound Library;Kinase Inhibitor Library;Anti-Cancer Compound Library;Autophagy Compound Library;Anti-Aging Compound Library;Anti-Blood Cancer Compound Library;
Related Small Molecules:DB0614;AT9283;Chiauranib;ENMD-2076 Tartrate;Barasertib-HQPA;AMG 900;SCH-1473759;BI-847325;CCT129202;PF 477736;CD532;ZM-447439;Palmatine;TAK-632;MK-8745;NU6140;Aurora kinase inhibitor-9;Aurora A inhibitor 1;Aurora Kinases-IN-2;Ilorasertib;PHA-680632;Aurora inhibitor 1;Hesperadin;Tozasertib;Alisertib;Aurora/LIM kinase-IN-1;KW-2449;Aurora kinase inhibitor-2;AKI603
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