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MRX-2843

CAS No. : 1429882-07-4

Biological Activity：MRX-2843 (UNC2371) is an orally active, ATP-competitive dual MERTK and FLT3 tyrosine kinases inhibitor (TKI) with enzymatic IC₅₀s of 1.3 nM for MERTK and 0.64 nM for FLT3, respectively.

Research Area：Cancer

Targets：FLT3

Related Screening Libraries:Drug Repurposing Compound Library Plus;Clinical Compound Library Plus;Bioactive Compound Library Plus;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;Anti-Cancer Compound Library;Clinical Compound Library;Drug Repurposing Compound Library;Orally Active Compound Library;Anti-Blood Cancer Compound Library;Anti-Prostate Cancer Compound Library;

Related Small Molecules:AT9283;(E/Z)-Zotiraciclib;Crotonoside;FLT3-IN-13;PDGFRα/FLT3-ITD-IN-2;FLT3/CDK4-IN-1;HP1142;ENMD-2076 Tartrate;ATH686;AZD2932;AKN-028 acetate;FLT3-IN-3;UNC2025 hydrochloride;Tandutinib;Gilteritinib-d8;PF 477736;(R)-3-Hydroxy Midostaurin;BSc5371;OTS447;PDGFRα/FLT3-ITD-IN-1;TAK-659 hydrochloride;FLT3-IN-4;JNJ-47117096 hydrochloride;FLT3-IN-14;MAX-40279 hemiadipate

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