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SJ988497
CAS No. : 2595365-41-4
Biological Activity：SJ988497 is a PROTAC JAK2 degrader. SJ988497 potently inhibits CRLF2-rearranged (CRLF2r) cell proliferation and degrades the CRBN neosubstrate GSPT1. SJ988497 consists of a Ruxolitinib (HY-50856) derivative, linker, and CRBN ligand Pomalidomide. SJ988497 can be used in the research of acute lymphoblastic leukemia (ALL).
Research Area：Cancer
Targets：JAK|PROTACs
Related Small Molecules:AZ-3;PROTAC Sirt2 Degrader-1;DB0614;JAK3/BTK-IN-1;AT9283;Benzene hexabromide;PROTAC VEGFR-2 degrader-2;(E/Z)-Zotiraciclib;dTAGV-1-NEG;CCT367766 formic;JAK-IN-10;Baricitinib-d3;JAK3-IN-6;HDAC6 degrader-1;PROTAC Axl Degrader 2;PhosTAC7;MS98;JPS014;Coumermycin A1;Deucravacitinib;PROTAC PARP1 degrader;MD-224;Momelotinib-3,3,5,5-d4;FKBP12 PROTAC dTAG-7;SJ10542;MS8815;RIP2 Kinase Inhibitor 4
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