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3,5-Bis(4-nitrophenoxy)benzoic acid
CAS No. : 173550-33-9
Biological Activity：3,5-Bis(4-nitrophenoxy)benzoic acid is an inhibitor of γ-secretase. 3,5-Bis(4-nitrophenoxy)benzoic acid causes a decrease in the released levels of Aβ42 and notch-1 Aβ-like peptide 25 (Nβ25). 3,5-Bis(4-nitrophenoxy)benzoic acid, as a marker for fetal hypothyroidism, is a 3,3’-diiodothyronine sulfate (T2S) cross-reactive material in maternal serum.
Research Area：Metabolic Disease
Targets：γ-secretase
Related Small Molecules:γ-Secretase modulator 4;ELN318463;Crenigacestat;Aβ42-IN-1 free base;Fosciclopirox;JNJ-40418677;gamma-secretase modulator 3;γ-Secretase modulator 11 hydrochloride;γ-Secretase modulator 12;Aβ42-IN-2;DAPT (GMP);BPN-15606;LY-411575 (isomer 3);BMS 433796;YO-01027 (GMP);BI-1408;Nirogacestat dihydrobromide;gamma-secretase modulator 1 hydrochloride;MRK-560;Semagacestat;Begacestat;GSM-1;Compound E;L-685458
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