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Vemurafenib-d5
CAS No. : 1365986-90-8
Biological Activity：Vemurafenib-d5 (PLX4032-d5) is the deuterium labeled Vemurafenib. Vemurafenib (PLX4032) is a first-in-class, selective, potent inhibitor of B-RAF kinase, with IC50s of 31 and 48 nM for RAFV600E and c-RAF-1, respectively[4]. Vemurafenib induces cell autophagy[5].
Research Area：Cancer
Targets：Autophagy|Raf
Related Small Molecules:Avutometinib;AZ 628;Everafenib;L-779450;Raf inhibitor 1;PLX-4720;RRD-251;B-Raf IN 8;TAK-632;Encorafenib;RAF mutant-IN-1;AD80;CCT241161;PLX7904;RAF-IN-1;EGFR/BRAFV600E-IN-1;MCP110;GDC-0879;B-Raf IN 1;R18;Rineterkib
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