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Tunicamycin
CAS No. : 11089-65-9
Biological Activity：Tunicamycin is a mixture of homologous nucleoside antibiotic that inhibits N-linked glycosylation and blocks GlcNAc phosphotransferase (GPT). Tunicamycin causes accumulation of unfolded proteins in cell endoplasmic reticulum (ER) and induces ER stress, and causes blocking of DNA synthesis and cell cycle arrest in G1 phase. Tunicamycin inhibits gram-positive bacteria, yeasts, fungi, and viruses and has anti-cancer activity[2][3].Tunicamycin increases exosome release in cervical cancer cells[4].
Research Area：Cancer|Infection|Inflammation/Immunology
Targets：Fungal|Influenza Virus|Bacterial|Antibiotic
Related Screening Libraries:Natural Product Library Plus;Bioactive Compound Library Plus;Anti-Infection Compound Library;Immunology/Inflammation Compound Library;Natural Product Library;Anti-Cancer Compound Library; Antiviral Compound Library;Antifungal Compound Library;Antibacterial Compound Library;Endoplasmic Reticulum Stress Compound Library;Antibiotics Library;Exosomes Compound Library;Microbial Metabolite Library;Anti-Cancer Natural Product Library;
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