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Indomethacin farnesil
CAS No. : 85801-02-1
Biological Activity：Indomethacin farnesil is an orally active prodrug of Indomethacin. Indomethacin (Indometacin) is a potent, blood-brain permeable and nonselective inhibitor of COX1 and COX2, with IC50s of 18 nM and 26 nM for human COX-1 and COX-2, respectively, in CHO cells. Indomethacin disrupts autophagic flux by disturbing the normal functioning of lysosomes[2].
Research Area：Inflammation/Immunology
Targets：Autophagy|COX
Related Small Molecules:Akt/NF-κB/JNK-IN-1;COX-2/5-LOX-IN-3;Ampyrone;COX-2-IN-24;Zaltoprofen-d7;α-Vitamin E-d6;1-Hydroxy-ibuprofen;Asaraldehyde;(-)-Epicatechin;20(S)-Ginsenoside Rg3;Ginsenoside Rd;Nimesulide D5;COX-2/5-LOX-IN-1;S-(+)-Marmesin;Tazofelone;Catechin-13C3;Diclofenac-d4;Proglumetacin;Ethoxycoronarin D;Phenidone;Iguratimod;Fenbufen-d9;COX-2-IN-6;Anti-inflammatory agent 9;Pentagamavunon-1;Aceclofenac
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