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PROTAC IRAK4 degrader-2
CAS No. : 2374122-27-5
Biological Activity：PROTAC IRAK4 degrader-2 (Compound 9) is a PROTAC-based IRAK4 degrader that affords potent IRAK4 degradation with a DC50 in peripheral blood mononuclear cells (PBMCs) cells of 151 nM. PROTAC IRAK4 degrader-2 induce a reduction of IRAK4 protein levels with a DC50 of 36 nM in PBMC cells. PROTAC IRAK4 degrader-2 also leads to the inhibition of multiple cytokines in PBMCs.
Research Area：Cancer|Inflammation/Immunology
Targets：PROTACs|IRAK
Related Small Molecules:PROTAC Sirt2 Degrader-1;DB0614;PROTAC VEGFR-2 degrader-2;dTAGV-1-NEG;CCT367766 formic;HDAC6 degrader-1;PROTAC Axl Degrader 2;PhosTAC7;MS98;JPS014;PROTAC PARP1 degrader;MD-224;FKBP12 PROTAC dTAG-7;IRAK4-IN-8;SJ10542;Edecesertib;MS8815;RIP2 Kinase Inhibitor 4;PROTAC EGFR degrader 7;SJ995973;CC-885-CH2-PEG1-NH-CH3;dFKBP-1;MI-389;BSJ-4-116;MS4078;PZ703b;DP-C-4;KB02-JQ1;QCA570;NJH-2-056
Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
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