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2-Hexyl-4-pentynoic acid
CAS No. : 96017-59-3
Biological Activity：2-Hexyl-4-pentynoic acid ((±)-2-Hexyl-4-pentynoic acid), valproic acid (VPA) derivative, exhibits potential roles of HDAC inhibition (IC50=13 µM) and HSP70 induction. Potent neuroprotective effects. 2-Hexyl-4-pentynoic acid causes histone hyperacetylation and protect against glutamate-induced excitotoxicity in cultured neurons.
Research Area：Neurological Disease
Targets：HDAC|HSP
Related Small Molecules:6BrCaQ;Pivanex;116-9e;Crotonoside;MPT0B390;RSC133;HDAC1/6-IN-1;Paeoniflorin;HDAC/HSP90-IN-4;Debio 0932;JPS014;HDAC-IN-4;MKT-077;Ethoxyquin;Cemdomespib;HDAC-IN-27;1-Alaninechlamydocin;SKLB-23bb;Tacedinaline;HPOB;HDAC-IN-28;CG347B;Tubacin;HDAC10-IN-1;Apatorsen;HS-131;CH5138303;HDAC6-IN-6
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