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Selpercatinib
CAS No. : 2152628-33-4
Biological Activity:Selpercatinib (LOXO-292) is a potent, selective RET kinase inhibitor with IC50 values of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M), and RET (G810R), respectively. Selpercatinib has anticancer activity[2].
Research Area:Cancer
Targets:RET
Related Screening Libraries:Drug Repurposing Compound Library Plus;FDA-Approved Drug Library Plus;FDA-Approved Drug Library Mini;Bioactive Compound Library Plus;Kinase Inhibitor Library;Protein Tyrosine Kinase Compound Library;FDA-Approved Drug Library;Anti-Cancer Compound Library;Drug Repurposing Compound Library;Orally Active Compound Library;FDA Approved & Pharmacopeial Drug Library;Anti-Lung Cancer Compound Library;Anti-Pancreatic Cancer Compound Library;Targeted Therapy Drug Library ;Targeted Diversity Library;Anti-Liver Cancer Compound Library ;Rare Diseases Drug Library;FDA-Approved Anticancer Drug Library;Human Metabolite Library;
Related Small Molecules:RET-IN-18;Zeteletinib;RET-IN-5;GSK3179106;Pyrazoloadenine;trans-Pralsetinib;PF 477736;BT-13;RET-IN-8;AD80;JNJ-38158471;Amuvatinib hydrochloride;RET-IN-11;TRK II-IN-1;RET-IN-10;RET-IN-17;RET-IN-7;RET-IN-13;TG101209;WHI-P180;TAS05567;RET-IN-14;FLT3/ITD-IN-4;Pz-1
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